Picture of  Lucile Fressigné

Lucile Fressigné PhD, MSc Postdoctoral Fellow, U of S

Areas of Interest

  • Molecular and cellular Biology
  • Genetics
  • Cancer research
  • Biochemical engineering, microbiology
  • Ecology community-based participatory research

About

Dr. Lucile Fressigné is a postdoctoral research associate at the Johnson Shoyama Graduate School of Public Policy, and is working in collaboration with Northern Policy Analytics. 

Lucile specializes in ecology, molecular and cellular biology. She has a PhD from Laval University with a doctoral dissertation exploring the regulation of small non-coding RNA in the nematode C. elegans (round worms). 

Lucile is currently leading research to estimate the grizzly bear and black bear population size in Yukon using non-invasive DNA based methods. As a pioneering researcher within the Yukon, she has extensive experience engaging with laboratories studying bears within Canada and internationally to exchange knowledge and technical support.

Lucile is also a former instructor for Biology at Yukon University and a former research student at the Curie Institute of Cancerology, a leading cancer research institute in France.

Lucile's postdoctoral research position is currently being funded by Mitacs. 

Designations

  • Ph.D. in Molecular and Cellular Biology, Laval University
  • M.Sc. in Biochemical Engineering, National Institute of Applied Sciences (France)

Awards

  • Enhancement Trust - Yukon Fish and Wildlife Management Board - 2020/2021
  • Scholarly Activity Grant - Yukon University - 2019/2020
  • Fellowship of Excellence from the Department of Molecular Biology, Medical Biochemistry, and Pathology - Laval University - 2015   
  • Fellowship of Excellence in graduate studies - Laval University - 2014

Select Publications

Papers

  • Fressigne L, Houle F, Bosse G, Li L, Landry-Proulx G, Michaud P, Gu W, Simard MJ. Under review. C. elegans PPM-2 regulates small RNAs function by stabilizing Argonaute proteins. Scientific Reports.
  • Fressigne L, Simard MJ. 2017. Biogenesis of small non-coding RNAs in animals. Medecine Sciences. 34(2):137-144. Article in French.
  • Quevillon-Huberdeau M, Zeitler DM, Hauptmann J, Bruckmann A, Fressigne L, Danner J, Piquet S, Strieder N, Engelmann JC, Jannot G, Deutzmann R, Simard MJ, Meister G. 2017. Phosphorylation of Argonaute proteins affects mRNA binding and is essential for microRNA-guided gene silencing in-vivo. EMBO. 36(14):2088-2106.
  • Wang C, Gupta P, Fressigne L, Bosse G, Wang X, Simard MJ, Hansen D. 2016. TEG-1 CD2BP2 controls miRNA levels by regulating miRISC stability in C. elegans and human cells. Nucleic Acids Research. 45(3):1488-1500.
  • Teske PR, Sandoval-Castillo J, Fressigne L, Beheregaray L. 2013. Ten microsatellite loci from an undescribed South Pacific sea squirt, Pyura sp., and their use in the detection of non-random mating. Molecular Ecology Resources. 13, 341-343.

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